Tarvitsen vähän apua noiden numeroiden tulkkauksessa kun ei oikein aukea, eli tässä ois tutkimus:
"BACKGROUND: Asthma exacerbations, most often caused by respiratory tract infections, are the leading causes of asthma morbidity and comprise a significant proportion of asthma-related costs. Vitamin D status might play a role in preventing asthma exacerbations.
OBJECTIVES: We sought to assess the relationship between serum vitamin D levels and subsequent severe asthma exacerbations.
METHODS: We measured 25-hydroxyvitamin D levels in sera collected from 1024 children with mild-to-moderate persistent asthma at the time of enrollment in a multicenter clinical trial of children randomized to receive budesonide, nedocromil, or placebo (as-needed beta-agonists): the Childhood Asthma Management Program. Using multivariable modeling, we examined the relationship between baseline vitamin D levels and the odds of any hospitalization or emergency department visit over the 4 years of the trial.
RESULTS: Thirty-five percent of all subjects were vitamin D insufficient, as defined by a level of 30 ng/mL or less 25-hydroxyvitamin D. Mean vitamin D levels were lowest in African American subjects and highest in white subjects. After adjusting for age, sex, body mass index, income, and treatment group, insufficient vitamin D status was associated with a higher odds of any hospitalization or emergency department visit (odds ratio, 1.5; 95% CI, 1.1-1.9; P = .01).
CONCLUSION: Vitamin D insufficiency is common in this population of North American children with mild-to-moderate persistent asthma and is associated with higher odds of severe exacerbation over a 4-year period."
Niin tuossa resultissa on toi odds ratio elikkä: (odds ratio, 1.5; 95% CI, 1.1-1.9; P = .01). Voisiko joku neuvoa että mitä mikin numero tossa meinaa? Kyl mää yleisesti ottaen ymmärrän tuon tutkimuksen, mutta olisi kiva saada valaistusta noihin numeroihin, että ymmärtäisisi vähän "syvällisemminkin".
"BACKGROUND: Asthma exacerbations, most often caused by respiratory tract infections, are the leading causes of asthma morbidity and comprise a significant proportion of asthma-related costs. Vitamin D status might play a role in preventing asthma exacerbations.
OBJECTIVES: We sought to assess the relationship between serum vitamin D levels and subsequent severe asthma exacerbations.
METHODS: We measured 25-hydroxyvitamin D levels in sera collected from 1024 children with mild-to-moderate persistent asthma at the time of enrollment in a multicenter clinical trial of children randomized to receive budesonide, nedocromil, or placebo (as-needed beta-agonists): the Childhood Asthma Management Program. Using multivariable modeling, we examined the relationship between baseline vitamin D levels and the odds of any hospitalization or emergency department visit over the 4 years of the trial.
RESULTS: Thirty-five percent of all subjects were vitamin D insufficient, as defined by a level of 30 ng/mL or less 25-hydroxyvitamin D. Mean vitamin D levels were lowest in African American subjects and highest in white subjects. After adjusting for age, sex, body mass index, income, and treatment group, insufficient vitamin D status was associated with a higher odds of any hospitalization or emergency department visit (odds ratio, 1.5; 95% CI, 1.1-1.9; P = .01).
CONCLUSION: Vitamin D insufficiency is common in this population of North American children with mild-to-moderate persistent asthma and is associated with higher odds of severe exacerbation over a 4-year period."
Niin tuossa resultissa on toi odds ratio elikkä: (odds ratio, 1.5; 95% CI, 1.1-1.9; P = .01). Voisiko joku neuvoa että mitä mikin numero tossa meinaa? Kyl mää yleisesti ottaen ymmärrän tuon tutkimuksen, mutta olisi kiva saada valaistusta noihin numeroihin, että ymmärtäisisi vähän "syvällisemminkin".
Vastaukset 3
Vanhimmat
... todennäköisyyslaskelmien numeroarvoilta.
Tosi luotettavan tahon puoleen käännyitkin. Siis noilla joillain oli suurempi riski joutua hospitaaliin tai emergenssi osastolle, tarkemmin sanottuna 1.5 kertainen niihin toisiin nähden. Noin siis tilastollisesti keskimäärin. Noi muut on tilastollisia tunnuslukuja. Luottamusväli on varmaan siis 1.1-1.9 ja p-arvo, jota on käytetty on 0.01. Jossei kukaan pätevämpi vastaa mitään niin googlaa tilastollisesta testaamisesta jotain tai laita tää kyssäri matikkapalstalle.
Ehkä suomi24:n Lääketiede-palsta voisi olla myös paikka, jossa asiasta tiedetään enemmän.