Tässäpä mielenkiintoinen tutkimus yrityksestä hoitaa matalaa t3:sta ja korkeaa rt3:sta aiheuttavaa ARF:ää tyroksiinilla. ei mennyt hyvin.
"Ultimately, disease-associated changes in deiodinase pathways can be so potent that thyroid hormone signaling is compromised both locally and systemically, as seen during nonthyroidal illness syndrome. This condition is present in about 75% of hospitalized patients (343) and is characterized by variable changes in circulating thyroid hormone levels according to the type and severity of illness, typically including a fall in serum T3 and a rise in serum rT3. It is controversial whether nonthyroidal illness syndrome is an adaptive response to catabolic stress or a pathological entity that should be treated with exogenous thyroid hormone (344,345). A number of controlled trials with thyroid hormone supplementation have shown no benefit (346) or, in one case, worsened outcome (347).", lähde http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647704/#B347
tutkimuksesta 347 (toiseksi mainittu) lyhyempi kooste: http://www.ncbi.nlm.nih.gov/pubmed/10620211/
Sieltä poimittu lause: "Mortality was higher in the thyroxine group than the control group (43 vs. 13%) and correlated with suppression of TSH."
"Ultimately, disease-associated changes in deiodinase pathways can be so potent that thyroid hormone signaling is compromised both locally and systemically, as seen during nonthyroidal illness syndrome. This condition is present in about 75% of hospitalized patients (343) and is characterized by variable changes in circulating thyroid hormone levels according to the type and severity of illness, typically including a fall in serum T3 and a rise in serum rT3. It is controversial whether nonthyroidal illness syndrome is an adaptive response to catabolic stress or a pathological entity that should be treated with exogenous thyroid hormone (344,345). A number of controlled trials with thyroid hormone supplementation have shown no benefit (346) or, in one case, worsened outcome (347).", lähde http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647704/#B347
tutkimuksesta 347 (toiseksi mainittu) lyhyempi kooste: http://www.ncbi.nlm.nih.gov/pubmed/10620211/
Sieltä poimittu lause: "Mortality was higher in the thyroxine group than the control group (43 vs. 13%) and correlated with suppression of TSH."
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