http://www.activeherb.com/science/sawp_science.shtml
Alla väitetään, että sahapalmu tiputtaa dht:tä siinä missä finasteridikin.
--cut/paste--
"If this hypothesis is to hold, one may expect that BPH patients may have reduced DHT levels after usage of saw palmetto. To test this idea, a group of researchers studied prostate samples obtained from BPH patients who have taken 320 mg standardized saw palmetto extract for 3 months. They analysed the concentration of T and DHT in various parts of the prostate gland1. What they saw was striking. In the so-called periurethral region, whose enlargement causes urinary obstruction, DHT level is at average 2363 pg/g in patients treated with saw palmetto whereas DHT level is at average 7317 pg/g in untreated patients. The DHT level reduction is statistically very significant (P‹ 0.001). Meanwhile, The level of T is increased to 1023 pg/g in treated patients from 615 pg/g in untreated patients. These results provided the key support on the hypothesis that saw palmetto can inhibit 5-alpha-reductase in patients and indeed reduce the DHT production.
These findings are confirmed by another independent study 2 in which BPH patients were randomized to receive either saw palmetto or placebo for 6 months. Here the levels of DHT in prostate were determined before and after trial in both saw palmetto and placebo groups. Again DHT levels were reduced significantly by 32% from 6.49 ng/g to 4.4 ng/g after saw palmetto treatment (P‹ 0.005) whereas no significant change in the placebo group.
Therefore, these results strongly suggest that saw palmetto can effectively reduce the level of DHT in patients with moderate BPH. This in turn may slow down the growth of prostate cells and thus relieve the symptoms of BPH. Saw palmetto thus may represent an efficient tool to maintain the DHT level in aging men.
Reference
1.Di Silverio F, Monti S, Sciarra A, Varasano PA, Martini C, Lanzara S, D'Eramo G, Di Nicola S, Toscano V. Effects of long-term treatment with Serenoa repens (Permixon) on the concentrations and regional distribution of androgens and epidermal growth factor in benign prostatic hyperplasia. Prostate. 1998 Oct 1;37(2):77-83.
2. Marks LS, Hess DL, Dorey FJ, Luz Macairan M, Cruz Santos PB, Tyler VE. Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens. Urology. 2001 May;57(5):999-1005. "
Alla väitetään, että sahapalmu tiputtaa dht:tä siinä missä finasteridikin.
--cut/paste--
"If this hypothesis is to hold, one may expect that BPH patients may have reduced DHT levels after usage of saw palmetto. To test this idea, a group of researchers studied prostate samples obtained from BPH patients who have taken 320 mg standardized saw palmetto extract for 3 months. They analysed the concentration of T and DHT in various parts of the prostate gland1. What they saw was striking. In the so-called periurethral region, whose enlargement causes urinary obstruction, DHT level is at average 2363 pg/g in patients treated with saw palmetto whereas DHT level is at average 7317 pg/g in untreated patients. The DHT level reduction is statistically very significant (P‹ 0.001). Meanwhile, The level of T is increased to 1023 pg/g in treated patients from 615 pg/g in untreated patients. These results provided the key support on the hypothesis that saw palmetto can inhibit 5-alpha-reductase in patients and indeed reduce the DHT production.
These findings are confirmed by another independent study 2 in which BPH patients were randomized to receive either saw palmetto or placebo for 6 months. Here the levels of DHT in prostate were determined before and after trial in both saw palmetto and placebo groups. Again DHT levels were reduced significantly by 32% from 6.49 ng/g to 4.4 ng/g after saw palmetto treatment (P‹ 0.005) whereas no significant change in the placebo group.
Therefore, these results strongly suggest that saw palmetto can effectively reduce the level of DHT in patients with moderate BPH. This in turn may slow down the growth of prostate cells and thus relieve the symptoms of BPH. Saw palmetto thus may represent an efficient tool to maintain the DHT level in aging men.
Reference
1.Di Silverio F, Monti S, Sciarra A, Varasano PA, Martini C, Lanzara S, D'Eramo G, Di Nicola S, Toscano V. Effects of long-term treatment with Serenoa repens (Permixon) on the concentrations and regional distribution of androgens and epidermal growth factor in benign prostatic hyperplasia. Prostate. 1998 Oct 1;37(2):77-83.
2. Marks LS, Hess DL, Dorey FJ, Luz Macairan M, Cruz Santos PB, Tyler VE. Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens. Urology. 2001 May;57(5):999-1005. "
Vastaukset 4
Vanhimmat
Juu se on tiedossa oleva asia että sahapalmussa on ainesosia jotka vaikuttavat samalla lailla kun finasteridi. Muistaakseni Suomessa Curbicin-nimisessä tuotteessa on tätä sahapalmua (sitä myydään laajentuneeseen eturauhaseen).
Jotkut uskovat että "luonnollinen" rohdosvalmiste aiheuttaisi vähemmän sivuvaikutuksia kun lääketieteellisesti valmistettu finasteridin kaltainen aine, mutta usein tietääkseni nämä rohdokset aiheuttavat enemmän sivuoireita koska niissä on satoja tai tuhansia erilaisia aineita eikä niitä tyypillisesti ole testattu yhtä huolellisesti kun lääkkeitä.
Vaikuttaa omalla kohdallani nyt siltä että sahapalmu voisi toimiakin.
Vedin sitä curbisalin muodossa ainakin kuukauden mutta muutama viikko sitten kävin ostamassa gefinareseptin, koska tuntui, että ohimoni vain harvenivat entisestään vaikka popsin sahapalmua.
Nyt kuitenkin gefinnaa reilu pari viikkoa syötyöni varsinkin harvempi ohimoni on kiistatta, selkeästi paremman näköinen. Ensimmäisenä veljeni kiinnitti tähän huomiota. Minulla on siis tosi lyhyt siili ja musta tukka, jolloin tukan harvuus näkyy tosi hyvin.
Gefina ei ole voinut tässä ajassa muutosta saada aikaan, joten sahapalmun luulisi laittaneen homman alulle.
Itse aion nyt palata sahapalmuun ja katsella, miten kehitys jatkuu. Siinä en nimittäin huomannut sivuoireita, gefinan kanssa jotain.
Myös soijalla on väitetty olevan samankaltaista vaikutusta kuin tällä sahapalmulla. Ihan hyvin voi toimiakin, itse ainakin mieluummin testaan luontaisvaihtoehdon ensin, nyt kun tilanne ei ole vielä paha. Kiitti vinkistä.
Itsekin olen ahkerasti testaillut luonnontuotteita. Söin carnosin-soyaa nelisen kuukautta, mutta koska se ei tuntunut ainakaan minulla mitään tekevän, jätin sen pois jo useampi kuukausi sitten.