" Taustaa: Hengitys ja muut oireet ovat usein liittyvät altistumiseen mikrobit läsnä vesi-vaurioitunut rakennuksia. Material and methods: We examined 82 consecutive patients referred to the Indoor Air Clinic, Helsinki University Hospital, due to symptoms suspected of having been caused by long-term exposure to water damage in the home or workplace. Materiaali ja menetelmät: Emme tutki 82 peräkkäistä potilasta saatettiin Indoor Air klinikka, Helsingin yliopistollinen sairaala, koska oireet epäillään aiheuttama pitkäaikainen altistuminen veden vahinkoja kotona tai työpaikalla. Exposure to water damage was assessed by building inspections and microbial analyses as needed. Altistuminen veden vahingot arvioitiin rakennuksen tarkastuksista ja mikrobien analyysejä tarvitaan. Bronchoalveolar lavage, lung function measurements, skin prick tests to inhalant allergens and radiological examinations were performed in all patients. Bronchoalveolar lavage, keuhkojen toiminta mittaukset, ihon prick-testit inhalant allergeenit ja radiologiset tutkimukset tehtiin kaikille potilaille. Leucocyte subsets in peripheral blood were analysed in 35 patients. Leucocyte aineistoluokkia reuna veren tutkittiin 35 potilaalla. Results: Marked water damage was detected in the homes or workplaces of 47 (59%) patients; the remaining 34 patients formed the control group. Tulokset: Marked vesivahingon havaittiin koteihin tai työpaikoille 47 (59%) potilailla, loput 34 potilasta muodostivat kontrolliryhmässä. The exposed group expressed more symptoms in total than the control group: fatigue, conjunctival symptoms, rhinitis with sinusitis, recurrent bronchitis and asthma were more common in the exposed group, but a significant difference was seen only for headache. Alttiina ryhmä ilmaista oireita yhteensä kuin kontrolliryhmässä: väsymys, sidekalvon oireita, riniitti kanssa Sinuiitti, toistuvaa bronkiitti ja astma olivat yleisempiä alttiina, mutta merkittävä ero havaittiin vain päänsärky. In BAL (bronchoalveolar lavage) samples, lymphocytes represented 25% of the total cell population in non-smoking-exposed patients compared with 12% in control patients (p=0.004). Vuonna BAL (bronchoalveolar lavage) näytteet, lymfosyytit edustaa 25% koko solun väestön savuttomia altistuneiden potilaiden verrattuna 12% valvonta-potilailla (p = 0,004). In peripheral blood, CD19 leucocytes were significantly decreased in the exposed group (7.5% versus 12.3%; p
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Patients referred to an indoor air health clinic: exposure to water-damaged buildings causes an increase of lymphocytes in bronchoalveolar lavage and a decrease of CD19 leucocytes in peripheral blood. by: Henrik Wolff, Helena Mussalo-Rauhamaa, Hanna Raitio, Peter Elg, Arto Orpana, Anneli Piilonen, Tari Haahtela Scandinavian journal of clinical and laboratory investigation (3 April 2009), pp. 1-8. Citation Format http://translate.google.fi/translate?hl=fi&langpair=en|fi&u=http://www.citeulike.org/user/Terkko/article/4285806&prev=/translate_s?hl=fi&q=CD19 verestä&tq=Blood CD19&sl=fi&tl=en
http://translate.google.fi/translate_s?hl=fi&q=CD19 verestä&um=1&ie=UTF-8&sl=fi&tl=en&tq=Blood CD19&ei=_psRStqNMMKF_Qab3cWxBA&sa=X&oi=clir_tip&ct=search_link&resnum=11
http://www.citeulike.org/user/Terkko/article/4285806 Patients referred to an indoor air health clinic: exposure to water-damaged buildings causes an increase of lymphocytes in bronchoalveolar lavage and a decrease of CD19 leucocytes in peripheral blood. by: Henrik Wolff, Helena Mussalo-Rauhamaa, Hanna Raitio, Peter Elg, Arto Orpana, Anneli Piilonen, Tari Haahtela Scandinavian journal of clinical and laboratory investigation (3 April 2009), pp. 1-8. "Background: Respiratory and other symptoms are often associated with exposure to microbes present in water-damaged buildings. Material and methods: We examined 82 consecutive patients referred to the Indoor Air Clinic, Helsinki University Hospital, due to symptoms suspected of having been caused by long-term exposure to water damage in the home or workplace. Exposure to water damage was assessed by building inspections and microbial analyses as needed. Bronchoalveolar lavage, lung function measurements, skin prick tests to inhalant allergens and radiological examinations were performed in all patients. Leucocyte subsets in peripheral blood were analysed in 35 patients. Results: Marked water damage was detected in the homes or workplaces of 47 (59%) patients; the remaining 34 patients formed the control group. The exposed group expressed more symptoms in total than the control group: fatigue, conjunctival symptoms, rhinitis with sinusitis, recurrent bronchitis and asthma were more common in the exposed group, but a significant difference was seen only for headache. In BAL (bronchoalveolar lavage) samples, lymphocytes represented 25% of the total cell population in non-smoking-exposed patients compared with 12% in control patients (p=0.004). In peripheral blood, CD19 leucocytes were significantly decreased in the exposed group (7.5% versus 12.3%; p