BBC:n sivulla linkki muille sivuille.
http://news.bbc.co.uk/1/hi/health/4546704.stm
Deadly fungus gene code cracked
Scientists have cracked the genetic code of a fungus responsible for deadly infections and allergic reactions.
Aspergillus fumigatus , which causes more infections than any other mould, is particularly dangerous to people with weakened immune systems.
Researchers at the Institute for Genomic Research hope their work could lead to better diagnostic tests, and treatments for fungal infections.
Their international collaboration is reported in the journal Nature.
This study does for the first time start to give an indication of why such closely related species in nature can have such different effects
Dr Paul Dyer
......................................
http://www.tigr.org/news/index.shtml
The Institute for Genomic Research
December 21, 2005 Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
http://www.tigr.org/news/pr_12_21_05.shtml
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
December 21, 2005
*snip*
It's a complex task. Suspect genes encode proteins involved in central metabolic pathways, cell signaling, cell wall biosynthesis, pigment biosynthesis, and secondary metabolite production. In other words, A. fumigatus's virulence genes are likely complex and mixed up with normal metabolic capabilities, Nierman says.
He and his colleagues now plan to systematically "knock out," or disable, genes that might make A. fumigatus infectious. Eventually, Nierman adds, this work could lead to better therapies for serious asthma, allergy, and other conditions.
........................
http://www.nature.com/nature/journal/v438/n7071/edsumm/e051222-09.html
Editor's Summary
22 December 2005
Genomes with influence
http://www.nature.com/nature/journal/v438/n7071/abs/nature04332.html
Letter
Nature 438, 1151-1156 (22 December 2005) doi:10.1038/nature04332
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
...............................
http://www.nature.com/nature/journal/v438/n7071/suppinfo/nature04332.html
e.g.:
Supplementary Text: Secondary Metabolites
http://www.nature.com/nature/journal/v438/n7071/suppinfo/nature04332.html
Table S1. Proteins implicated in A. fumigatus pathogenicity.
http://news.bbc.co.uk/1/hi/health/4546704.stm
Deadly fungus gene code cracked
Scientists have cracked the genetic code of a fungus responsible for deadly infections and allergic reactions.
Aspergillus fumigatus , which causes more infections than any other mould, is particularly dangerous to people with weakened immune systems.
Researchers at the Institute for Genomic Research hope their work could lead to better diagnostic tests, and treatments for fungal infections.
Their international collaboration is reported in the journal Nature.
This study does for the first time start to give an indication of why such closely related species in nature can have such different effects
Dr Paul Dyer
......................................
http://www.tigr.org/news/index.shtml
The Institute for Genomic Research
December 21, 2005 Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
http://www.tigr.org/news/pr_12_21_05.shtml
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
December 21, 2005
*snip*
It's a complex task. Suspect genes encode proteins involved in central metabolic pathways, cell signaling, cell wall biosynthesis, pigment biosynthesis, and secondary metabolite production. In other words, A. fumigatus's virulence genes are likely complex and mixed up with normal metabolic capabilities, Nierman says.
He and his colleagues now plan to systematically "knock out," or disable, genes that might make A. fumigatus infectious. Eventually, Nierman adds, this work could lead to better therapies for serious asthma, allergy, and other conditions.
........................
http://www.nature.com/nature/journal/v438/n7071/edsumm/e051222-09.html
Editor's Summary
22 December 2005
Genomes with influence
http://www.nature.com/nature/journal/v438/n7071/abs/nature04332.html
Letter
Nature 438, 1151-1156 (22 December 2005) doi:10.1038/nature04332
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
...............................
http://www.nature.com/nature/journal/v438/n7071/suppinfo/nature04332.html
e.g.:
Supplementary Text: Secondary Metabolites
http://www.nature.com/nature/journal/v438/n7071/suppinfo/nature04332.html
Table S1. Proteins implicated in A. fumigatus pathogenicity.
Vastaukset 5
Vanhimmat
odotettavissa, että meillä joiden immunnipuolustusjärjestelmän on heikentänyt kosteusvauriokohteen homeet ja jota on pahentanut TTL:n altistuskokeet, syntyy myös infektio-sairaus Aspergillus fumigatuksesta.
Eräällä meistä on jo sienikasvustoa sisällään, mutta en muista, että oliko se nimenomaan aspergillusta. Tiedät ketä tarkoitan, voisitko kertoa sen uudestaan, vaikka tällä palstalla?
Kyllä se vain niin on, että TTL:n "final solution" on tappaa meidät näillä altistuskokeillaan.
Kerron muuten huomenna SUUREN uutisen. TTL on nyt sitten lopullisesti kusessa!
Pekka Nikkola
''Kyllä se vain niin on, että TTL:n "final solution" on tappaa meidät näillä altistuskokeillaan.''
Ei Allergiasairaala eikä TTL suostu tekemään kemikaalialtistusta, jotta erään henkilön sairaus saataisiin todettua! Eräs lääkäri on yrittänyt saada ko. testauksen, mutta ei onnistu.
Syy voi tietysti olla se, että selviäisi jotain muuta, kuin somatisaatiohäiriö....
Mitenköhän pitkään pystyvät olemaan tietämättömiä, kun tavallinen 'maija meikäläinenkin' lukee sujuvasti tutkimusta, mistä ko. tahot eivät tiedä mitään.....
>Kerron muuten huomenna SUUREN uutisen.
Hakeudut vihdoin psykiatriseen hoitoon?
älä luule luuta lihaks`ja kissanpäätä paistikkaaks`.
Työterveyslaitoksen psykiatri on tutkinut mielenterveyteni ja todennut sen olevan kunnossa. Minulla on näyttää paperit siitä! Onko Sinulla näyttää papereita siitä, et ole mielenterveydellisesti sairas? Uskon, että sinulla saattaisi olla vaikeuksia saada tällainen paperi.
Työterveyslaitoksen psykiatri ei sanonut minua hulluksi edes siinä vaiheessa, kun sanoin hänelle, että TTL pilaa tahallisesti altistuskokeillaan meidän terveyden. Hän ei voinut tehdä, niin koska tiesi, että minä puhun totta.
Pyydän Sinua ystävällisesti poistumaan häiritsemästä meitä. Sinulla ei ole mitään annettavaa meille kosteusvauriomikrobeista sairastuneille!
Pekka Nikkola