"A common adage holds that food is the medicine for anorexia nervosa. Weight gain alone does often normalize mood in anorexia nervosa, but it can be hard to accomplish and frequently requires hospitalization. Although certain psychiatric medications can cause weight gain in the general population, none has had this effect with malnourished anorexic patients. Recent exciting studies suggest that olanzapine (Zyprexa) and other medications in this class may finally offer a drug that can help some low-weight anorexia nervosa patients. Olanzapine lessens anxiety and obsessional thinking, and some anorexic patients find they feel less paralyzed due to rigid thinking and behavior on this medication.
Olanzapine was originally marketed for schizophrenia, and although anorexia nervosa is not a psychotic illness, there is certainly a delusional quality about feeling fat when you are dangerously starved. Clinicians find that on olanzapine, some people with anorexia nervosa are better able to grasp their situation and engage in treatment. Low-dose, short-term use may facilitate that elusive transition from low to healthy weight for some people, speeding the initial steps to recovery and sometimes averting hospitalization.
Once someone with anorexia nervosa has been successful in restoring weight, maintaining those gains is the next hurdle. Unfortunately, immediate relapse is common. Here's where fluoxetine enters the picture. Although this drug does not help anorexia nervosa while the patient's weight is low, after the weight has been regained, fluoxetine may significantly lessen the risk of relapse when used as part of a comprehensive treatment program. "
Olanzapine was originally marketed for schizophrenia, and although anorexia nervosa is not a psychotic illness, there is certainly a delusional quality about feeling fat when you are dangerously starved. Clinicians find that on olanzapine, some people with anorexia nervosa are better able to grasp their situation and engage in treatment. Low-dose, short-term use may facilitate that elusive transition from low to healthy weight for some people, speeding the initial steps to recovery and sometimes averting hospitalization.
Once someone with anorexia nervosa has been successful in restoring weight, maintaining those gains is the next hurdle. Unfortunately, immediate relapse is common. Here's where fluoxetine enters the picture. Although this drug does not help anorexia nervosa while the patient's weight is low, after the weight has been regained, fluoxetine may significantly lessen the risk of relapse when used as part of a comprehensive treatment program. "
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