mielilalalääkkeiden haitoista

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Mielialalääkkeiden haitoista:

Nopealla tiedelehtien selailulla löytyivät nämä tuoreet mielialalääkkeiden vakavista haitoista ja puutteista kertovat artikkelit:

Psychosis Associated With Modafinil and Shift Work. Am J Psychiatry 162:1983, October 2005
http://ajp.psychiatryonline.org/cgi/content/short/162/10/1983?rss=1

Wishful thinking: antidepressant drugs in childhood depression Br J Psychiatry.2005; 187: 304-305
http://bjp.rcpsych.org/cgi/content/short/187/4/304?rss=1

Psychological therapy must accompany antidepressants in young people BMJ 2005;331:714 (1 October)
"The guideline makes it clear that medication is not the first line treatment for children and young people with depression. Antidepressants should only be considered when psychological treatments are not working, and should only be used in combination with a psychological treatment," explained David Cottrell, professor of child and adolescent psychiatry at the University of Leeds.
Fluoxetine was recommended as the only antidepressant for which trials show that its benefits outweigh the risks, with sertra-line or citalopram recommended as second line treatments. The guideline cautioned that paroxetine and venlafaxine, tri-cyclic antidepressants, and St John's wort should not be used in children or young people.
http://bmj.bmjjournals.com/cgi/content/full/331/7519/714-b?rss

Study finds that costly new antipsychotics offer few benefits over traditional drugs BMJ 2005;331:717 (1 October)
The findings show that all the drugs helped to control symptoms of schizophrenia, but 74% of participants stopped taking their drug because of discomfort or specific side effects, such as involuntary movements, jerkiness, tremors, or akathisia.
Jeffrey Lieberman, the trial’s principal investigator and chairman of the Department of Psychiatry at Columbia University and director of the New York State Psychiatric Institute, said, "The message is the glass is half full. The drugs work but they are not satisfactory to many patients, and three quarters of the people in our study voted with their feet and discontinued the drugs."
http://bmj.bmjjournals.com/cgi/content/full/331/7519/717?rss

Lilly to add suicide risk warning to drug label
Eli Lilly and Co. on Thursday said it will add strong warnings to its label for Strattera, used to treat attention-deficit/hyperactivity disorder, including the risk of suicidal thoughts among children and adolescents.
Strattera will now carry a "black box" warning, the strongest required by U.S. regulators. Such warnings typically hurt sales of products by raising concern among doctors and patients about the safety of a drug.
The Indianapolis drugmaker said a review of clinical trials data identified a small but statistically significant increased risk of suicidal thoughts among children and adolescents treated with Strattera.
http://today.reuters.co.uk/news/newsarticle.aspx?type=healthNews&storyid=2005-09-29T204048Z_01_BAU945277_RTRIDST_0_HEALTH-LILLY-DC.XML


Aika paljon siis kirjoitetaan mielialalääkkeiden vaaroista. Päätelkää nyt sitten näistä artikkeleista onko syytä huoleen vaiko ei. Sen tiedän reaalielämästä potilasyhdistyksessäni, että oikean lääkkeen etsiminen on melkoinen stressin paikka mielenterveyspotilaalle.

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