Company description
Orion is a globally operating Finnish company developing pharmaceuticals and diagnostic tests - a builder of well-being. Orion develops, manufactures and markets human and veterinary pharmaceuticals, active pharmaceutical ingredients and diagnostic tests. The company is continuously developing new drugs and treatment methods. Pharmaceutical R&D focuses on central nervous system drugs, oncology and critical care drugs, and Easyhaler® pulmonary drugs. Orion's net sales in 2012 amounted to EUR 980 million and the company had about 3,500 employees. Orion's A and B shares are listed on NASDAQ OMX Helsinki.
Structural Chemistry and Bioanalytics is part of Analytics in Pharmaceutical Sciences and is responsible for bioanalytics and structural elucidation for Orion R&D projects with a focus in discovery and early development. Main tasks of units:
• Development of quantitative bioanalytical methods and applying them for quantification of drugs and their metabolites in biological fluids and different tissues
• Providing analytical expertise in the characterization and identification of the drug metabolites as well as identification of disintegration products of new chemical entities
• Providing structural information for syntheses intermediate and final products
• Metabolite identification associated with the use of radioisotope labeled analogues of the drug candidates
Job description
An eligible applicant has a strong knowledge of identification of biotransformation products (drug metabolites) in vitro and in vivo. As an expert, you will provide and interpret metabolism data for projects in cooperation with medicinal chemists, specialists in drug metabolism and pharmacokinetics (DMPK) and safety fields. You will plan, guide and report studies and compile various documents for regulatory purposes as an expert in your own area. In everyday work, you will also advice work of Research Associates in the laboratory.
Requirements:
• Ph.D. in chemistry, pharmacy or technical sciences or a related field is required
• Excellent capabilities of using modern analytical methods, equipment and techniques (e.g. liquid chromatography-high resolution mass spectrometry)
• A thorough knowledge of organic analytical chemistry and influence of structure of functional groups to metabolism and safety
• Experience in practical laboratory work and an ability to integrate and apply knowhow in drug research and development
We expect our research scientists to be able to work both independently and in research teams. Good interaction skills and ability to perform under pressure are highly valued. Excellent oral and written communication skills in English are a must. We appreciate experience in the pharmaceutical industry.
We offer:
We offer challenging and interesting tasks in discovery and development, state-of-the-art facilities and a chance to join a dynamic team building tomorrow’s well-being. The position offers generous health and welfare benefits and support in relocation.
Additional information on the position:
Mika Pykäläinen, tel. 358 50 966 4664
- 1-5 July at 9-15
- 5-9 August at 9-15
Sari Häkkinen, tel. 358 50 966 2019
- 24-26 July at 12-15
Please apply here: http://service.joberate.com/redirect/url/bfd8-51-93-1c-1dd7ab
Application period ends: 13.08.2013
Orion is a globally operating Finnish company developing pharmaceuticals and diagnostic tests - a builder of well-being. Orion develops, manufactures and markets human and veterinary pharmaceuticals, active pharmaceutical ingredients and diagnostic tests. The company is continuously developing new drugs and treatment methods. Pharmaceutical R&D focuses on central nervous system drugs, oncology and critical care drugs, and Easyhaler® pulmonary drugs. Orion's net sales in 2012 amounted to EUR 980 million and the company had about 3,500 employees. Orion's A and B shares are listed on NASDAQ OMX Helsinki.
Structural Chemistry and Bioanalytics is part of Analytics in Pharmaceutical Sciences and is responsible for bioanalytics and structural elucidation for Orion R&D projects with a focus in discovery and early development. Main tasks of units:
• Development of quantitative bioanalytical methods and applying them for quantification of drugs and their metabolites in biological fluids and different tissues
• Providing analytical expertise in the characterization and identification of the drug metabolites as well as identification of disintegration products of new chemical entities
• Providing structural information for syntheses intermediate and final products
• Metabolite identification associated with the use of radioisotope labeled analogues of the drug candidates
Job description
An eligible applicant has a strong knowledge of identification of biotransformation products (drug metabolites) in vitro and in vivo. As an expert, you will provide and interpret metabolism data for projects in cooperation with medicinal chemists, specialists in drug metabolism and pharmacokinetics (DMPK) and safety fields. You will plan, guide and report studies and compile various documents for regulatory purposes as an expert in your own area. In everyday work, you will also advice work of Research Associates in the laboratory.
Requirements:
• Ph.D. in chemistry, pharmacy or technical sciences or a related field is required
• Excellent capabilities of using modern analytical methods, equipment and techniques (e.g. liquid chromatography-high resolution mass spectrometry)
• A thorough knowledge of organic analytical chemistry and influence of structure of functional groups to metabolism and safety
• Experience in practical laboratory work and an ability to integrate and apply knowhow in drug research and development
We expect our research scientists to be able to work both independently and in research teams. Good interaction skills and ability to perform under pressure are highly valued. Excellent oral and written communication skills in English are a must. We appreciate experience in the pharmaceutical industry.
We offer:
We offer challenging and interesting tasks in discovery and development, state-of-the-art facilities and a chance to join a dynamic team building tomorrow’s well-being. The position offers generous health and welfare benefits and support in relocation.
Additional information on the position:
Mika Pykäläinen, tel. 358 50 966 4664
- 1-5 July at 9-15
- 5-9 August at 9-15
Sari Häkkinen, tel. 358 50 966 2019
- 24-26 July at 12-15
Please apply here: http://service.joberate.com/redirect/url/bfd8-51-93-1c-1dd7ab
Application period ends: 13.08.2013
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